Alibaba DAMO Academy and partners developed a liver cancer diagnostic AI model named DAMO LiON, which was published in Nature Medicine. In a two-month real-world trial involving over 10,000 patients, the model identified 15 previously missed malignant tumors, mostly around 1 cm in diameter, helping patients receive timely treatment. It reduced doctors’ reading time by 27% and improved their tumor detection sensitivity by 11.5%, while also enabling junior doctors to reach senior-level diagnostic skills. The model uses an improved network architecture that considers the relationship between lesions and the liver as a whole while preserving local texture and boundary details, and it can integrate different enhanced CT scan phases to better detect lesions in complex liver conditions.